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1,2,7,8,13,13bβ,14,14aα-Octahydro-1β-vinyl-2α-(β-D-glucopyranosyloxy)-5H-indolo[2,3-a]pyrano[3,4-g]quinolizine-5-one
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Strictosamide is a natural alkaloid isolated from the herbs of Nauclea latifolia, it exhibits the activity of anti-inflammatory. In vitro and in vivo, strictosamide has no effection on kidney Na(+),K(+)-ATPase, but in vivo it produces
an increase of Na+,K+-ATPase activity of brain, these findings indicate that
the compound may be related to the induction of α2 isoform of Na+,K+-ATPase.
Furthermore strictosamide has nonsignificant effection on brain, but inhibite the in vitro and in vivo Mg2+-ATPase activity on kidney.
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