7,4'-Dihydroxy-2',3'-dimethoxyisoflavene
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Haginin A is a natural compound isolated from the aerial parts of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity and mushroom tyrosinase inhibitory activity. Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of tyrosinase and TRP-1 production.
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