CBL0137 hydrochlori...

CBL0137 hydrochloride

CBL0137 hydrochloride

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Negotiable

  • Min.Order :0
  • Purity: ≥98%

Keywords

CBLC137 CBL-0137

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  • Appearance:Crystalline Solid
  • Application:For research use only.
  • PackAge:50 mg
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Details:

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death.

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