Epacadostat

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0	Negotiable

Min.Order :0
Purity: ≥95%

Keywords

IDO inhibitor 1 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-

Quick Details

Appearance:White to off-white solid powder
Application:For research use only.
PackAge:100 mg
ProductionCapacity:
Storage:Store at -20°C
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Details:

Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells.

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