4-Methylumbelliferyl b-D-galactopyranoside-6-sulphate

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Purity: ≥98%

Keywords

4-MU β-D-galactopyranoside-6-sulfate 4-Methylumbelliferyl Gal-6S

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Appearance:White to Off-white Solid
Application:For research use only.
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Storage:Store at -20°C under inert atmosphere
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4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (4-MU-Gal-6S) is a fluorogenic substrate for N-acetylgalactosamine-6-sulphatase (GALNS). 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence intensity increases as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient.

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