CasNo.136470-79-6,ent-Abacavir,2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)-(136470-79-6) Suppliers

0	Negotiable

Min.Order :0
Purity: 97%

Keywords

(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol (1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol

Quick Details

Appearance:Off-White to Pale Yellow Solid
Application:Anti-HIV Agents
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ProductionCapacity:
Storage:Store at -20°C
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We provide customized and high-quality ent-Abacavir product for your project.

Details:

ent-Abacavir (Abacavir EP Impurity A) is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.