Fialuridine 5'-Monophosphate

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1-(2-Deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione

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Fialuridine 5'-Monophosphate (FIAUMP) is the phosphorylated derivative and major metabolite of the antiviral agent Fialuridine. Studies show that purified mammalian DNA polymerases were able to incorporate FIAUMP into the nascent DNA chain during in vitro DNA synthesis.

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