8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer, sodium salt
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Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to cGMP or Sp-cGMPS, it has more lipophilic and membrane-permeant properties.
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