Sumatriptan D6 3-[2-(Dimethyl-d6-amino)-ethyl]-N-methyl-1H-indole-5-methanesulfonamide
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Sumatriptan-[d6] is the labelled analogue of Sumatriptan. Sumatriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist that acts selectively at 5HT1 receptors. It is a sulfonamide triptan with vasoconstrictor activity. It selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system, thus constricts cerebral blood vessels. It may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater. It is a medication used for the treatment of migraine headaches.
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