rac Ketorolac-[d4]

rac Ketorolac-[d4]

rac Ketorolac-[d4]

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  • Min.Order :0
  • Purity: >98%

Keywords

5-Benzoyl-2,3-dihydro-1H-(pyrrolizine-d4)-1-carboxylic Acid (+/-)-Ketorolac-d4

Quick Details

  • Appearance:Beige Solid
  • Application:For research use only.
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  • Storage:Store at-20°C
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Details:

Labelled rac Ketorolac. Ketorolac, a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug. It shows inhibition of eicosanoid formation in HEL cells (COX-1) and LPS-stimulated Mono Mac 6 cells (COX-2), but does not significantly inhibit NO accumulation in supernatants of LPS-stimulated RAW 264.7 cells. It significantly inhibits thymidine incorporation of human osteoblasts (hOBs) upon 24 hours treatment in a dose-dependent manner, and inhibits proliferation and arrests cell cycle at G0/G1 phase in hOBs.

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