5-[(3,4,5-(Trimethoxy-13C3)yphenyl)methyl]-2,4-pyrimidinediamine 2,4-Diamino-5-[3',4',5'-(trimethoxy-13C3)benzyl]pyrimidine
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Labelled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections. It caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. It binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF).
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