1-Naphthalenylsulfonyl-Ile-Trp-aldehyde

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Purity: ≥95%

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N-(1-Naphthalenylsulfonyl)-Ile-Trp-aldehyde Pentanamide, N-[(1S)-1-formyl-2-(1H-indol-3-yl)ethyl]-3-methyl-2-[(1-naphthalenylsulfonyl)amino]-, (2S,3S)-

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Application:For research use only.
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1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a potent, reversible, selective and cell-permeable cathepsin L inhibitor with an IC50 of 1.9 nM. It inhibits the release of bone Ca2+ and hydroxyproline in vitro and is useful in the treatment of osteoporosis.

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