Buforin I

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Purity: ≥90% by HPLC

Keywords

H-Ala-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-Gly-Asn-Tyr-OH L-alanyl-glycyl-L-arginyl-glycyl-L-lysyl-L-glutaminyl-glycyl-glycyl-L-lysyl-L-valyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanyl-glycyl-L-leu...

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Buforin I is a 39-amino acid AMP that was first isolated from the stomach tissue of the Asian toad Bufo gargarizans. Compared with other amphibian AMPs, such as magainin 2, buforin I shows much stronger antimicrobial activities in vitro against a broad spectrum of microorganisms. Buforins have anti-endotoxin and anticancer activities.

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