Details:

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molar Mass	138.12
Density	1.44
Melting Point	158-161°C(lit.)
Boling Point	211°C(lit.)
Flash Point	157 °C
JECFA Number	958
Water Solubility	1.8 g/L (20 ºC)
Solubility	Slightly soluble in water, easily soluble in ethanol and ether. 1 gram of this product can be dissolved in 460 ml of water, 15 ml of hot water, 2.7 ml of alcohol, 3 ml of acetone, 42 ml of chloroform, 3 ml of ether, 135 ml of benzene, 52 ml of turpentine
Vapor Presure	1 mm Hg ( 114 °C)
Vapor Density	4.8 (vs air)
Appearance	White needle crystal
Color	White to off-white
Maximum wavelength(λmax)	['210nm, 234nm, 303nm']
Merck	14,8332
BRN	774890
pKa	2.98(at 25℃)
PH	3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Storage Condition	2-8°C
Stability	Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.
Sensitive	Light Sensitive
Refractive Index	1,565
MDL	MFCD00002439
Physical and Chemical Properties	Character: White needle-like crystal or monoclinic prisms, with spicy taste. melting point 159 ℃ boiling point 211 ℃ relative density 1.443 solubility slightly soluble in water, soluble in acetone, turpentine, ethanol, ether, benzene and chloroform.
Use	The pharmaceutical industry is used to make antipyretic, analgesic, anti-inflammatory, diuretic and other drugs, the dye industry is used to make azo direct dyes and acid mordant dyes, also used in spices and so on

Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition.

Introduction

Open Data Unverified Data

salicylic acid, also known as the acid, for white crystalline powder, odorless, the taste of the first slightly bitter and then turn into Xin. Found in nature in willow bark, white-bead leaves, and sweet birch. Chemical formula C6H4(OH)(COOH), melting point 157-159 ℃, in the light gradually color change. The relative density was 1.44. The boiling point is about 211 °c/2.67kPa. 76 degrees C sublimation. Under atmospheric pressure, it is rapidly decomposed into phenol and carbon dioxide by heating. Soluble in ethanol, ether, chloroform, benzene, acetone, turpentine, not soluble in water. 1g of salicylic acid can be dissolved in 460ml of water, 15ml of boiling water, 2.7ml of ethanol, 3ml of acetone, 3ml of ether, 42ml of chloroform, 135ml of benzene, 52ml of turpentine, about 60ml of glycerol and 80ml of petroleum ether, respectively. Adding sodium phosphate, borax etc. can increase the solubility of salicylic acid in water. The pH of the salicylic acid aqueous solution was 2.4. Salicylic acid with ferric chloride in water produces a special purple color.

 

Important raw materials for organic synthesis

Open Data Unverified Data

• salicylic acid is an important organic synthetic raw material, widely used in medicine, pesticide, rubber, dye, food and perfume industry. In the pharmaceutical industry, salicylic acid for the production of the main drugs are sodium salicylate, oil of wintergreen (methyl salicylate), aspirin (acetylsalicylic acid), salicylic acid amine, phenyl salicylate and so on. In the dye industry for the production of mordant yellow, direct yellow 3GN, direct yellow GR, direct Brown 3GN, acid mordant Brown G, acid mordant yellow GG, acid yellow and other dyes. In the production of pesticides, salicylic acid is used for the synthesis of isopropyl salicylate, an intermediate of The organophosphorus insecticides isocarbophos and methyliisophos, and 4-hydroxycoumarin, an intermediate of the rodenticide and rodenticide. In the rubber industry as scorch retarder and the production of ultraviolet absorber and foaming agent. Spices raw materials, preparation of methyl salicylate, Ethyl salicylate, etc.; Food preservatives, the use of its sodium salt, now some countries have been banned; Methyl salicylate can be used as a mouth cleaner, such as toothpaste spices.
• salicylic acid has the ability to kill bacteria, 2.5% alcohol solution (called salicylic acid) commonly used as the treatment of tinea Manus and tinea pedis external medicine, can also be formulated into ointment use. Sodium salicylate may be used as a food preservative or preservative, and may also be used in the formulation of toothpastes, mouthwashes, and the like. Salicylic acid has antipyretic and analgesic effects, can treat rheumatism. Its various esters are useful as pharmaceuticals and fragrances. Methyl salicylate has a pleasant fragrance of wintergreen and is used in the preparation of perfumes and soap essences. Methyl salicylate applied to the skin, can penetrate into the muscle and release salicylic acid and local pain, and thus can also be used for the treatment of pain, contusion, sprain and other external drugs. Isoamyl salicylate has a orchid-like aroma, and benzyl salicylate has a faint aroma, which can be used to prepare perfume or soap essence. Phenyl salicylate, commonly known as Salo, is hydrolyzed to phenol and salicylic acid in the intestine and is an effective intestinal preservative. Another drug related to salicylic acid is p-aminosalicylic acid (PAS for short, see "p-aminosalicylic acid"), whose sodium and calcium salts are used as anti-tuberculosis drugs for Acute exudative tuberculosis and mucosal tuberculosis, is a weak antibacterial agent, the role of only 2% of streptomycin, often combined with streptomycin, isoniazid, in order to enhance the efficacy. Acetylating it can make aspirin.

Chemical properties

Open Data Unverified Data

• salicylic acid, also known as sulinic acid, is more acidic than benzoic acid, darkened in the sun, iron ions into a purple-red chelate, and ferric chloride reaction is purple, unstable to heat, it is easily decarboxylated to phenol by heating to 200 °c. In nature, salicylic acid exists in the form of methyl ester in birch bark oil, and the content can reach 96%. Also present in cinnamon oil, violet oil, wintergreen oil. Free salicylic acid is only present in small amounts in plants.
• salicylic acid has a dual nature of phenol and carboxylic acid. Sublimation when heated, rapid heating, the decomposition of phenol and carbon dioxide. Reaction with sodium hydroxide, hydroxyl and carboxyl groups are neutralized, the formation of double salt; But with sodium carbonate, only the carboxyl group is neutralized to form a single salt. When reacting with an alcohol or a phenol, the corresponding salicylate can be formed; When acting with a carboxylic acid or an acid anhydride, the corresponding carboxylate can be formed. This product is toxic, stimulate the skin, mucous membranes, can react with the body tissue protein, it is corrosive, on the other hand, it can be sterilized. Rat oral LD501100 ~ 1600mg/kg. Storage is stable, but the powder can produce an explosion when mixed with air.
• It is industrially prepared by reacting phenol sodium salt with carbon dioxide under heating and pressure (Kolbe-Schmitt reaction). First, phenol is neutralized with sodium hydroxide to form phenol sodium salt, then, carbon dioxide is absorbed at 105 Pa ° C. Under 4-7 × 125 (4-7 atmospheres) to form phenyl sulfonate, which is rearranged to form sodium salicylate and acidified to form salicylic acid.

 

important raw materials for organic synthesis	salicylic acid is an important raw material for organic synthesis, widely used in medicine, pesticide, rubber, dye, food and fragrance industries. In the pharmaceutical industry, salicylic acid for the production of the main drugs are sodium salicylate, oil of wintergreen (methyl salicylate), aspirin (acetylsalicylic acid), salicylic acid amine, phenyl salicylate and so on. In the dye industry for the production of mordant yellow, direct yellow 3GN, direct yellow GR, direct Brown 3GN, acid mordant Brown G, acid mordant yellow GG, acid yellow and other dyes. In the production of pesticides, salicylic acid is used for the synthesis of isopropyl salicylate, an intermediate of The organophosphorus insecticides isocarbophos and methyliisophos, and 4-hydroxycoumarin, an intermediate of the rodenticide and rodenticide. In the rubber industry as scorch retarder and the production of ultraviolet absorber and foaming agent. Spices raw materials, preparation of methyl salicylate, Ethyl salicylate, etc.; Food preservatives, the use of its sodium salt, now some countries have been banned; Methyl salicylate can be used as a mouth cleaner, such as toothpaste spices. FIG. 1 shows the structural formula of salicylic acid. salicylic acid has the ability to kill bacteria, 2.5% alcohol solution (called salicylic acid) commonly used as the treatment of tinea Manus and tinea pedis external medicine, can also be formulated into ointment use. Sodium salicylate may be used as a food preservative or preservative, and may also be used in the formulation of toothpastes, mouthwashes, and the like. Salicylic acid has antipyretic and analgesic effects, can treat rheumatism. Its various esters are useful as pharmaceuticals and fragrances. Methyl salicylate has a pleasant fragrance of wintergreen and is used in the preparation of perfumes and soap essences. Methyl salicylate applied to the skin, can penetrate into the muscle and release salicylic acid and local pain, and thus can also be used for the treatment of pain, contusion, sprain and other external drugs. Isoamyl salicylate has a orchid-like aroma, and benzyl salicylate has a faint aroma, which can be used to prepare perfume or soap essence. Phenyl salicylate, commonly known as Salo, is hydrolyzed to phenol and salicylic acid in the intestine and is an effective intestinal preservative. Another drug related to salicylic acid is p-aminosalicylic acid (PAS for short, see "p-aminosalicylic acid"), whose sodium and calcium salts are used as anti-tuberculosis drugs for Acute exudative tuberculosis and mucosal tuberculosis, is a weak antibacterial agent, the role of only 2% of streptomycin, often combined with streptomycin, isoniazid, in order to enhance the efficacy. Acetylating it can make aspirin.
physical properties	white crystalline powder, odorless, with slightly bitter taste before turning into octensive. Found in nature in willow bark, white-bead leaves, and sweet birch. Chemical formula C6H4(OH)(COOH), melting point 157-159 ℃, in the light gradually color change. The relative density was 1.44. The boiling point is about 211 °c/2.67kPa. 76 degrees C sublimation. Under atmospheric pressure, it is rapidly decomposed into phenol and carbon dioxide by heating. Soluble in ethanol, ether, chloroform, benzene, acetone, turpentine, not soluble in water. 1g of salicylic acid can be dissolved in 460ml of water, 15ml of boiling water, 2.7ml of ethanol, 3ml of acetone, 3ml of ether, 42ml of chloroform, 135ml of benzene, 52ml of turpentine, about 60ml of glycerol and 80ml of petroleum ether, respectively. Adding sodium phosphate, borax etc. can increase the solubility of salicylic acid in water. The pH of the salicylic acid aqueous solution was 2.4. Salicylic acid with ferric chloride in water produces a special purple color.
pharmacological effects	salicylic acid is widely used, eczema, psoriasis, acne, dandruff may be used salicylic acid. Salicylic acid concentration in 3% ~ 6% can be used to exfoliate, more than 6% is destructive to the tissue. Below 40% concentration is suitable for the treatment of corns, thick cocoon, virus warts. Salicylic acid can also be added in the treatment of acne and anti dandruff drugs. Now a lot of well-known cosmetics add salicylic acid ingredients: 1993 CLINIQUE first launched containing 1% salicylic acid ingredients of the soft renewal of the water cream, immediately become one of the most successful CLINIQUE products; in SK-II, 1.5%, BHA was added to the original Pitera formula, and the effect of salicylic acid in treating pores and cutin was compared with the shell egg, which caused the market boom; open-shelf pathway of the popular product of the skin essence cream also contains 1.5% BHA ingredients. However, due to the high concentration of salicylic acid has a certain degree of harm, cosmetics containing salicylic acid concentration is generally limited between 0.2% ~ 1.5%, containing salicylic acid cosmetics must be added warning signs to determine the safety of long-term use, and not for children under 3 years of age.
cosmetic effect comparison with fruit acid	salicylic acid (BHA) is extracted from willow bark and Ilex leaves, also known as plant acid; acid (AHA) is extracted from sugar cane; It is an acid extracted from two different raw materials. Both can control oil, exfoliation, remove acne, narrow pores, light. The concentration of more than 50% of the acid can only be operated by a dermatologist, and salicylic acid, regardless of the concentration of the skin, are classified as medical treatment, it is worth noting that a small number of people are not suitable for the use of any concentration of salicylic acid, so the general beauty room can not be implemented, in the beauty room to implement the concentration of 40% or less of the fruit acid is allowed by law, in contrast, fruit acid is much safer than salicylic acid. As for the effect, salicylic acid is only locked in the superficial stratum corneum, but only plays a role of simple treatment and blocking, changing the skin is only temporary, and the acid enters the dermis to fundamentally change the skin, it can be cured, as for the formation of dermal damage, the role of salicylic acid is unable to do so, so salicylic acid can not be called "salicylic acid skin change", can only be called "salicylic acid treatment". The safety and effect of salicylic acid and acid are different, because the acid is not toxic, can be used from low to high (8%-15%-20%-30%-40%), slow adaptation is not burn the skin, disfigurement and any side effects. And salicylic acid is toxic, too high concentration is not suitable for use on the face, there is a certain concentration limit, the concentration of 3%-6% of salicylic acid can be used to exfoliate, more than 6% of the skin corrosive, 40% high concentration of salicylic acid with strong keratolytic properties.
precautions for use	for general skin care, a small number of users, should not have systemic side effects. However, for a large range (greater than 30% of the total body area) or long-term use of salicylic acid, special attention should be paid to the toxic effect of salicylic acid. Including tinnitus, dizziness, burnout, Nausea and electrolyte imbalance, should immediately stop using. Salicylic acid can cause contact dermatitis. After large-area use and absorption, salicylic acid can appear systemic poisoning symptoms, such as dizziness, confusion, shortness of breath, persistent tinnitus, severe or persistent Head Pain, tingling. With diabetes, peripheral vascular disease, or infants, the use of salicylic acid 25%-60% cream or ointment, salicylic acid 15%-50% cream, salicylic acid 17% gel, salicylic acid 13.6%-26% solution should be carefully considered, it may cause inflammation or ulcers, or even death; For dermatitis or skin infections, the use of salicylic acid 25%-60% cream or ointment, salicylic acid 40%-50% cream, also need to pay attention.
Use	salicylic acid, also known as O-Hydroxybenzoic acid (o-hydroxybenzoic acid), is an important raw material for organic synthesis. In the production of pesticides, for the synthesis of organophosphorus insecticides isocarbophos, isosoraphos methyl intermediate isopropyl salicylate and rodenticide rodenticide, rodenticides intermediate 4-hydroxycoumarin; In the pharmaceutical industry, salicylic acid in addition to its own use as Disinfection preservative, but also as acetylsalicylic acid (aspirin) and other drugs intermediates; It is also an important raw material for dyes, spices, rubber and other industries. It is mainly used as the raw material of aspirin drugs and the raw material of pesticide isocarbophos and other products, and can also be used in the dye industry, refined chemical reagents and so on The pharmaceutical industry is used to make antipyretic, analgesic, anti-inflammatory, diuresis and other drugs, dye industry for the production of azo direct dyes and acid mordant dyes, also used in spices and so on used as complexing indicator and preservative salicylic acid is a medicine, perfume, dye, rubber additives and other important raw materials of fine chemicals. In the pharmaceutical industry, salicylic acid itself is used as a Disinfection antiseptic, for local keratinosis and skin fungal infection. As a pharmaceutical intermediate, it is used for the production of zhitongling, urea, acetylsalicylic acid (aspirin), sodium salicylate, Salicylamide, glibenclamide, Niclosamide, phenyl salicylate, ethyl p-hydroxybenzoate, bismuth subsalicylate, sulfasalazine and other drugs. In the dye industry, it is used to produce dyes such as direct yellow GR, direct Tan BL, direct Tan RT, acid medium brown G, acid medium yellow GG, etc. Various esters of salicylic acid can be used as a perfume, for example, methyl salicylate can be used as an oral perfume for toothpaste and the like, and other flavoring and food spices and the like. In the rubber industry for the production of scorch retarder, UV absorber and foaming additives. Salicylic acid can also be used as a phenolic resin curing agent, a pulp preservative for textile printing and dyeing, a swelling agent (dye accelerator) for dyeing synthetic fibers, etc. aluminum, boron, cerium, copper, iron, lead, manganese, mercury, nickel, silver, titanium, tungsten, vanadium, hyposulfite, nitrate and nitrite were tested. Determination of aluminum, copper, iron, thorium, titanium and uranium. Standard for alkaline and iodometric titration. Fluorescent indicator. Complexation indicator. determination of aluminum, boron, cerium, copper, iron, lead, manganese, mercury, silver, titanium, tungsten, vanadium, sulfite, nitrate and nitrite. Precipitation of thorium allows the separation of thorium from cerium and other rare earth elements, and the separation of zirconium and titanium. Fluorescent indicator; Preservative; Complexation indicator. Anti-inflammatory inhibitors of epoxy synthase activity. Determination of aluminum, boron, cerium, copper, iron, lead, manganese, mercury, silver, titanium, tungsten, vanadium, sulfite, nitrate and nitrite. Precipitation of thorium allows the separation of thorium from cerium and other rare earth elements, separation of zirconium and titanium, fluorescent indicator, Preservatives, complexing indicators.
production method	phenol reacts with sodium hydroxide to form sodium phenolate. After dehydration by distillation, carboxylation reaction is carried out with carbon dioxide, sodium salicylate was prepared and then acidified with sulfuric acid to obtain crude product. The crude product is refined by sublimation to obtain the finished product. Raw material consumption quota: phenol (98%)704kg/t, caustic soda (95%)417kg/t, sulfuric acid (95%)500kg/t, carbon dioxide (99%)467kg/t. The preparation method is obtained by carboxylation of phenol sodium salt with carbon dioxide and acidification. With phenol and liquid caustic soda made of phenol sodium salt solution, vacuum drying, and then slowly at 100 deg C into the dry carbon dioxide, when the pressure reaches 0.7 ~ 0.8MPa, stop through carbon dioxide, the temperature was increased to 140-180 °c. After the completion of the reaction, add water, sodium salicylate solution After decolorization, filtration, and sulfuric acid acidification, namely precipitation of salicylic acid, after filtration, washing, drying to obtain the finished product.

 

 

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 

  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.