(-)-Huperzine A ...

(-)-Huperzine A    102518-79-6
(-)-Huperzine A    102518-79-6
(-)-Huperzine A    102518-79-6
(-)-Huperzine A    102518-79-6
(-)-Huperzine A    102518-79-6

(-)-Huperzine A 102518-79-6

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 1.0000 -10.0000

  • Min.Order :1 Kilogram
  • Purity: >99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Selagine 5,9-Methanocycloocta[b]pyridin-2(1H)-one,5- amino-11-ethylidene-5,6,9,10-tetrahydro-7- methyl-,(5R,9R,11E)- 5,9-Methanocycloocta[b]pyridin-2(1H)-one,5- amino-11-ethylidene-5,6,9,10-tetrahydro-7- methyl-,(5R,9R,11E)-

Quick Details

  • Appearance:White
  • Application:Can effectively prevent the elderly brain neurasthenia, restore brain nerve function, activation of brain nerve transmission material
  • PackAge:In plastic outside weave or according to your request
  • ProductionCapacity:500|Kilogram|Week
  • Storage:-15°C
  • Transportation:We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.?

Superiority:

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details:

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Boling Point 505.0±50.0 °C(Predicted)
Specific Rotation(α) D -147° (c = 0.36 in CH3OH) (Ayer); D24.5 -150.4° (c = 0.498 in MeOH) (Liu)
Solubility Easily soluble in chloroform, soluble in methanol and ethanol, slightly soluble in water
Appearance Crystallization (propanol)
Color White to Almost white
pKa 12.25±0.60(Predicted)
Storage Condition Keep in dark place,Inert atmosphere,2-8°C
Refractive Index 1.626
MDL MFCD01714949
Physical and Chemical Properties From the plant of the family of taxiaceae, Chian Tower, Huperzinaserrata(Thumb.), Trev
Use Can effectively prevent the elderly brain neurasthenia, restore brain nerve function, activation of brain nerve transmission material

clarity of acidic solution

take this product 5mg, add 0.lmol/L hydrochloric acid solution 5m I dissolved, the solution should be clear.

Related substances

take this product, add 0.01mol/L hydrochloric acid solution to dissolve and make every 1 ml containing 0.lmg solution, as a test solution; Precision take the right amount, with O. 1mol/L hydrochloric acid solution was quantitatively diluted to prepare a solution containing 2.5ug per 1m = l as a control solution. According to the chromatographic conditions under the content determination item, 20 u1 of the test solution and the control solution are accurately measured and injected into the human liquid chromatograph respectively, and the chromatogram is recorded to 2 times of the retention time of the main component chromatographic peak. If there are impurity peaks in the chromatogram of the test solution, the sum of each impurity peak area shall not be greater than the main peak area of the control solution (2.5%).

examination

  • Related substances take this product fine powder, add 0.Olmol/L hydrochloric acid solution to dissolve Huperzine A and make a solution containing Huperzine A per 1 ml of 20, filtered, take the continued filtrate as a test solution; Precision children take appropriate children, with 0.Olmol/L hydrochloric acid solution is set and diluted to prepare a solution containing 0.8ug of Huperzine A per 1 ml, which is used as the control solution ^ As the chromatographic conditions under the content determination item, 50 u1 of the test solution and the control solution were respectively injected into the human liquid chromatograph, and the chromatogram was recorded to 2 times of the retention time of the main component peak. If there are impurity peaks in the chromatogram of the test solution, the sum of each impurity peak area shall not be greater than the main peak area of the control solution (0.2) except the chromatographic peak before the relative retention time is 4.0%.
  • 1 tablet of this product was placed in a 10ml measuring flask, and an appropriate amount of 0.0lmol/L hydrochloric acid solution was added. The Olmol/L hydrochloric acid solution is diluted to the scale, shaken well, filtered, and the filtrate is taken and the content is determined according to the method under the content determination item, which shall comply with the regulations (General rule 0941).
  • dissolution of this product, according to the dissolution and release determination method (General 0931 third method), with 0.100ml of 1 mol/L hydrochloric acid solution is the dissolution medium, and the rotation speed is 50 rpm, and the operation is carried out according to law. After 30 minutes, 10ml of the solution is taken, filtered, and the chromatographic conditions under the item of content determination are taken, the continuous filtrate 50 u1 was accurately measured, and human was injected into the liquid chromatograph, and the chromatogram was recorded, the dissolution medium was added to dissolve and quantitatively dilute to prepare a solution containing about 0.5ug of Huperzine A per 1 ml, which was determined by the same method. According to the external standard method, the dissolution amount of each tablet is calculated by the peak area, and the limit is 80% of the labeled amount, which shall be in accordance with the provisions.
  • others shall be in accordance with the relevant provisions under the item of tablets (General rule 0101).

Content determination

Take 20 tablets of this product, precision weighing, fine grinding, precision weighing appropriate amount (equivalent to Huperzine A 100ug), put it in a 20ml measuring flask, add 0.Olmol/L hydrochloric acid solution appropriate amount, ultrasonic to dissolve Huperzine A, with 0.Olmol/L hydrochloric acid solution is diluted to the scale, shaken, filtered, and the filtrate is taken as the test solution, according to the chromatographic conditions under the item of Huperzine A content determination, precise injection of 50ul into the liquid chromatograph, record the chromatogram; Another Huperzine A reference, precise weighing, add 0.Olmol/L hydrochloric acid solution was dissolved and diluted quantitatively to prepare a solution containing 5ug per lml, which was determined by the same method. According to the external standard method to calculate the peak area, that is.

examination

  • Related substances take an appropriate amount of the contents of this product and add O.Olmol/L hydrochloric acid solution Huperzine A was dissolved and diluted to make a solution containing Huperzine A of 20ug per 1 ml, filtered, and the continued filtrate was taken as the test solution. Olmol/L hydrochloric acid solution a solution containing 0.8ug of Huperzine A per 1 ml was prepared by diluting the solution with sodium chloride as a control solution. According to the chromatographic conditions under the content determination item, 50 u1 of the test solution and 50 u1 of the control solution are accurately measured and injected into the human liquid chromatograph respectively, and the chromatogram is recorded to 2 times of the retention time of the main component peak. If there are impurity peaks in the chromatogram of the test solution, the sum of each impurity peak area shall not be greater than the main peak area of the control solution (0.2) except the chromatographic peak before the relative retention time is 4.0%.
  • Content uniformity take 1 capsule of this product, pour the contents into a 10ml expensive bottle, and use a small amount of O.Olmol/L hydrochloric acid solution to wash the capsule shell, wash into the flask, plus 0.Olmol/L hydrochloric acid solution appropriate amount, ultrasonic to dissolve Huperzine A, with 0. The Olmol/L gold acid solution is diluted to the scale, shaken well, filtered, and the filtrate is taken and the content is determined according to the method under the item containing children's determination, which shall comply with the regulations (General rule 0941).
  • dissolution of this product, according to the dissolution and release determination method (General 0931 third method), with 0.100ml of 1 mol/L hydrochloric acid solution was used as the dissolution medium, the rotation speed was 35 revolutions per minute, and the operation was carried out according to law. After 30 minutes, 10ml of the solution was taken and filtered. According to the chromatographic conditions under the content determination item, the filtrate 50 u1 was accurately measured and injected into the human liquid chromatograph, and the chromatogram was recorded, the dissolution medium is added to dissolve and quantitatively dilute to prepare a solution containing about 0.5ug per 1 ml, which is determined by the same method, and the dissolution amount of each particle is calculated by the peak area according to the external standard method. The limit is 75% of the labeled amount and shall be in accordance with the provisions.

 

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.

 

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