Proteinase K powder Endopeptidase K CAS 39450-01-6
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Product Name: Proteinase K
CAS: 39450-01-6
MF: C29H27N2O12P
MW: 626.504641
EINECS: 254-457-8
Melting point: 200-205 °C
Boiling point: 492.7±45.0 °C
Density: 1.108±0.06 g/cm3
Storage temp.: Inert atmosphere,Room Temperature
Appearance: White Powder
Description:
Proteinase K, an extracellular endopeptidase is synthesized by the mold, Tritirachium album Limber. Proteinase K belongs to a new subfamily of the subtilisins. It is a 277 amino acid protein and is characterized with an unhydrolyzed protein chain and autolyzed polypeptide chains.
Uses:
Useful for the proteolytic inactivation of nucleases during the isolation of DNA and RNA.
Removes endotoxins that bind to cationic proteins such as lysozyme and ribonuclease A.
Reported useful for the isolation of hepatic, yeast, and mung bean mitochondria
Determination of enzyme localization on membranes
Treatment of paraffin embedded tissue sections to expose antigen binding sites for antibody labeling.
Digestion of proteins from brain tissue samples for prions in Transmissible Spongiform Encephalopathies (TSE) research.
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