N-Bromosuccinimide N-bromobutanimide 1-Bromopyrrolidine-2,5-dione
Superiority
Product Name: N-Bromosuccinimide
Synonyms: 1-Bromo-2,5-pyrrolidinedione, NBS, N-bromobutanimide, N-бромбутанимид;2,5-PYRROLIDINEDIONE, 1-BROMO-;1-BROMO-2,5-PYRROLIDINEDIONE;AKOS BBS-00004413;bromosuccinimide;BROMOSUCCINIMIDE-N;SUCCINIMIDE, N-BROMO-;SUCCINBROMIDE
CAS: 128-08-5
MF: C4H4BrNO2
MW: 177.98
EINECS: 204-877-2
Product Categories: Nitrogen cyclic compounds;Medical Intermediates;Biochemistry;Bromination;Halogenation;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry
Mol File: 128-08-5.mol
N-Bromosuccinimide Chemical Properties
Melting point 175-180 °C (dec.)(lit.)
Boiling point 221.4°C (rough estimate)
density 2.098
vapor pressure 14.8 hPa (20 °C)
refractive index 1.6060 (estimate)
storage temp. 0-6°C
solubility 14.8g/l (decomposition)
pka -2.78±0.20(Predicted)
form Crystalline Powder
color White to light yellow
Water Solubility Soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.
Sensitive Moisture Sensitive
Merck 14,1438
BRN 113916
Stability: Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.
InChIKey PCLIMKBDDGJMGD-UHFFFAOYSA-N
CAS DataBase Reference 128-08-5(CAS DataBase Reference)
NIST Chemistry Reference 2,5-Pyrrolidinedione, 1-bromo-(128-08-5)
EPA Substance Registry System N-Bromosuccinimide (128-08-5)
Safety Information
Hazard Codes C,Xn
Risk Statements 22-34-36/37/38
Safety Statements 26-36/37/39-45-37/39
RIDADR UN 3261 8/PG 2
WGK Germany 3
Hazard Note Harmful
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29251995
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
N-Bromosuccinimide Usage And Synthesis
Chemical Properties white to light yellow crystalline powder
Uses N-Bromosuccinimide is a brominated succinimide used as a chemical reagent in radical substitution and electrophilic addition reactions in organic synthesis.
Uses NBS, is a chemical reagent used in organic chemistry in electrophilic addition reactions and radical substitution
Uses In bromination of olefins; in oxidation of alcohols to aldehydes and ketones and of aldehydes to acid bromides.
Definition ChEBI: A five-membered cyclic dicarboximide compound having a bromo substituent on the nitrogen atom.
Safety Profile Poison by intraperitoneal route. An irritating poison to skin, eyes, and mucous membranes. Reacts explosively with adme, dtallyl sulfide, and hydrazine hydrate. Explosive reaction with propiononitrile after heating to 105℃ for 24 hours. Violent reaction with dtbenzoyl peroxide + 4-tok acid. When heated to decomposition it emits toxic fumes of Brand NOx. See also BROMIDES and NITROGEN MONOXIDE.
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