- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,D/P,T/T
Keywords
Fisetin(6CI) Flavone, 3,3',4',7-tetrahydroxy- (8CI) 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-benzopyran-4-one
Quick Details
- Appearance: yellow to brown crystalline powder
- Application: intermediate, medicine
- PackAge:25kg/drum
- ProductionCapacity:100|Kilogram|Week
- Storage: Sealed in dry,Store in freezer,under -20℃
- Transportation:normal
Superiority:
WLP Ingredient Inc was formerly known as Green Valley Biochemical, which was founded in Hong Kong in 2013 and WLPI was officially registered in 2019. In 2023, it reached a long-term strategic cooperation agreement with a local factory of plant extract. which already got HAHAL,KOSHER,ISO9001,ISO2200,HACCP,CGMP
Now it has developed into a comprehensive enterprise integrating R&D, production and sales. And after years of market accumulation and in response to customer needs, we have close cooperation in various fields and production such as human APIs, veterinary APIs, food additives, feed additives, vitamins, amino acids, etc
In the course of business, our company has always adhered to the principle of integrity first and won the praise of our customers. we hope that in the days to come,we can become your important partner and create a better future together
| Q1:Can i get some samples |
| A:Yes, we can provide 10-20 g sample for your testing, please contact us for more details. |
| Q2:What’s your MOQ |
| A:Our MOQ is 1kg. (Packed in aluminum foil bag) |
| Q3:How can I Buy |
| A:Proforma invoice will be sent first after confirmation of your purchase order,enclosed our bank information.Payment by T/T,L/C, or Paypal. |
| Q4:How can you confirm your quality If problem happens,how you treat with your client |
| A:You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and to get the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. |
| Q5:How do you treat with quality complaint |
| All of products are strictly tested by our QC, and confirmed by QA. We do test for products to make sure all of them are qualified. In case any quality problem is confirmed to be caused by us,we will replace the goods or refund your payment immediately. |
| Q6:What's the delievry time |
| A:Usually 3 working days for small orders,and large orders need to be checked based on different products. |
Details:
Fisetin powder cas 528-48-3 is a kind of natural flavonoid compound extracted from plants such as Anacardiaceae sycamore. It is also present in vegetables and fruits such as apples, persimmons, grapes, kiwi, strawberries, onions and cucumbers. It has antioxidant, anti-inflammatory and other pharmacological properties.
| Product Name: |
Fisetin Powder |
| Formula: |
C15H11ClO5 |
| Purity | 99% |
| Apperance: | Powder |
| Color: | Light brown yellow fine powder |
| Solubility: | Soluble in water |
| Storage: | Store in a cool dry place |
1.Anti-oxidation
Fisetin powder cas 528-48-3 is a bioflavonoid antioxidant that can help maintain glutathione levels and mitochondrial function in the presence of oxidative stress. It has the potential to cross the blood-brain barrier, which may help maintain neuronal function.
Fisetin can support the body's antioxidant pool by directly scavenging free radical activity and enhancing glutathione levels. In vitro studies have shown that fisetin can support glutathione, a very active antioxidant naturally present in the human body, by supplying cells with cysteine (a building block of glutathione) or by enhancing glutathione synthesis. glutathione. Fisetin may help regulate the production of many proteins involved in protecting the body from oxidative stress and maintaining redox homeostasis (the balance between the rate of free radical production and the rate of scavenging of various antioxidants).
2 Antitumor
In recent years, the role of fisetin in antitumor has attracted people's attention. Studies have shown that fisetin can exert anti-tumor effects by inducing tumor cell apoptosis, affecting tumor cell signal transduction pathways, inhibiting tumor cell proliferation, and inhibiting tumor cell migration and invasion.
Fisetin induces tumor cell apoptosis mainly by activating Caspase, down-regulating BIRC8 and Bcl2L2, and inhibiting COX-2.
The natural product fisetin can inhibit the growth and spread of tumor cells through various pathways. At the same time, fisetin has the characteristics of wide distribution in nature, less toxic and side effects, and multi-channel effects. Human health career services.
3 Anticancer effect
The researchers used the sumac extract containing fisetin, flavonoids, thioflavin and raspberry to compound the drug carrier to obtain a composition with anticancer activity. The activity experiment showed that the sumac extract has anti-human lung cancer. Cells, against uterine cancer cells, against human skin cancer cells and against human colon cancer cells. Its main mechanism is to induce the organ differentiation of cancer cells into normal cells by transforming cancer cell genes.
Fisetin is the most typical active substance in the flavonoids of fisetin, which can effectively inhibit the proliferation of prostate cancer cells and induce their apoptosis. In human lung cancer cells, fisetin can reduce the production of MMPs by inhibiting the MAP kinase and NF-κB pathways. And it can promote the proliferation of breast cancer, cervical cancer, blood cancer and other cells and promote apoptosis. Therefore, fisetin is considered as a potential anticancer agent.
Fisetin powder cas 528-48-3 is mainly used in healthcare products.
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