(Cys18)-Atrial Natr...

(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat)

(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat)

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  • Purity: 95%

Keywords

C-ANF (4-23) H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 (Disulfide bridge: Cys4-Cys15)

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(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat) binds with high affinity to about 99% of ANF receptors in isolated rat perfusion kidneys. It competes effectively for binding sites with bioactive atrial peptides but has no agonist or antagonist effect on cGMP generation in cultured vascular smooth muscle and endothelial cells.

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