(Ser8)-GLP-1 (7-36)...

(Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

(Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

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  • Purity: 95%

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(Ser79)-Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat) H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

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Serine substitution of alanine significantly improves the plasma stability of GLP-1(7-36) amide to DPP IV, but does not affect its insulinotropic activity. This may indicate that the modification can improve the potential of GLP-1 in the treatment of type 2 diabetes.

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