Catestatin (human)

Catestatin (human)

Catestatin (human)

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H-Ser-Ser-Met-Lys-Leu-Ser-Phe-Arg-Ala-Arg-Ala-Tyr-Gly-Phe-Arg-Gly-Pro-Gly-Pro-Gln-Leu-OH L-seryl-L-seryl-L-methionyl-L-lysyl-L-leucyl-L-seryl-L-phenylalanyl-L-arginyl-L-alanyl-L-arginyl-L-alanyl-L-tyrosyl-glycyl-L-phenylalanyl-L-arginyl-glycyl-L-prolyl-glycyl-L-prolyl-L-glutaminyl-L-l...

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Catestatin, an inhibitory peptide of catecholamine release, corresponds to human chromogranin A (CHGA) 370-390. Reduced catestatin expression may increase the risk of hypertension. In Chga-/- mice rescue of elevated blood pressure to normalcy was achieved by exogenous substitution of catestatin or transgenic expression of human CHGA.

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