Gastric Inhibitory ...

Gastric Inhibitory Polypeptide (1-30) amide (porcine)

Gastric Inhibitory Polypeptide (1-30) amide (porcine)

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Keywords

Glucose-Dependent Insulinotropic Polypeptide (1-30) amide (porcine) H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-NH2

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It is a fully glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42). It is a weak inhibitor of gastric acid secretion and a strong stimulator of insulin. The site responsible for insulinotropic activity is apparently located between residues 19 and 30 of GIP.

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