Q-VD-OPH

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Purity: >98%

Keywords

Q-VD-OPH Quinoline-Val-Asp-Difluorophenoxymethylketone

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Appearance:White to Off-white Solid Powder
Application:For research use only.
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Storage:Store at -20°C
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Details:

QVD-OPH, also known as Quinoline-Val-Asp-Difluorophenoxymethylketone, is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 (IC50 = 25nm), caspase-1 (IC50 = 50nM), caspase-8 (IC50 = 100nM) and caspase-9 (IC50 = 430nM). It can be used in Alzheimer's studies relating to caspase-6, the cysteinyl protease involved in neurodegenerative conditions. As well it is an intermediate in the formation of Palinavir, a potent HIV protease inhibitor.

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