S-Trityl-L-cysteine

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Purity: ≥ 98% (HPLC)

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S-(Triphenylmethyl)-L-cysteine

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Appearance:White to off-white powder
Application:For research use only.
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Storage:Store at 2-8 °C
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S-Trityl-L-cysteine is a cell-permeable, potent and selective inhibitor of mitotic kinesin Eg5, a protein required for establishing and maintaining a bipolar spindle. S-Trityl-L-cysteine inhibits basal and microtubule-activated ATPase activity of Eg5 (IC50 = 1 mM and 140 nM, respectively). S-Trityl-L-cysteine was shown to induce mitotic arrest in HeLa cells with an IC50 of 700 nM.

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