Z-Ile-Leu-aldehyde

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Min.Order :0
Purity: ≥95%

Keywords

Z-IL-CHO GSI-XII

Quick Details

Appearance:White to off-white solid
Application:Gamma Secretase Inhibitors and Modulators
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Storage:Store in a cool and dry place and at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
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Details:

Z-Ile-Leu-aldehyde ia a cell-permeable and reversible inhibitor that inhibits γ-secretase and Notch signaling. It induces apoptosis of murine MOPC315.BM myeloma cells with high Notch activity in vitro. It has potent anti-MM activity and reduces osteolytic lesions in vivo.

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