(-)-Neplanocin A

(-)-Neplanocin A

(-)-Neplanocin A

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Negotiable

  • Min.Order :0
  • Purity: ≥98%

Keywords

NPC-A (-)-9-(trans-2,trans-3-Dihydroxy-4-(hydroxymethyl)-cyclopent-4-enyl)-adenine

Quick Details

  • Appearance:Colorless Acicular Crystal
  • Application:Antibiotics, Antineoplastic
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  • Storage:Store at -20°C
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Details:

(?)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively).

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