(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one 2',4'-dihydroxy-6'-methoxychalcone
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Cardamonin is a naturally occuring chalcone initially isolated from the seeds of Amomum subulatum and subsequently from other zingiberous plant species. Cardamonin exhibits its antiinflammatory activity via suppression of p65NF-κB nuclear translocation and I-κBɑ phosphorylation. Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.
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