Lonchocarpol A Senegalensin
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6,8-Diprenylnaringenin is a hop prenylflavonoid that is a breast cancer resistance protein (BCRP/ABCG2) inhibitor. It inhibits ABCG2 mediated efflux of mitoxantrone and 3H-methotrexate transport (IC50 = 0.41 μM). 6,8-Diprenylnaringenin has some estrogenic activity, but its potency is less than 1% of 8-pentenyl naringin.
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