(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan 1H,3H-Furo[3,4-c]furan, 1-(3,4-dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-, [1S-(1α,3aα,4α,6aα)]-
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Magnolin is a major pharmacologically active ingredient derived from Shin-i, the dried flower buds of Magnolia fargesii (Magnoliaceae) that has been used for the treatment of empyema, nasal congestion, sinusitis, and allergic rhinitis. Magnolin inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
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