(S)-2-Hydroxyglutaric acid L-2-Hydroxyglutaric acid
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(2S)-2-Hydroxyglutaric acid, an epigenetic modifier and putative oncometabolite of kidney cancer, inhibits histone demethylase, thereby promoting histone methylation. It inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively.
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