2-Desamino-2-methylaminopterin

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Purity: ≥95%

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dmAMT (4-(((4-amino-2-methylpteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid

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2-Desamino-2-methylaminopterin is an antifolate, and its polyglutamates are more potent than monoglutamate against three key enzymes of folate metabolism. It inhibits tumor cell growth in culture but is only a weak inhibitor of dihydrofolate reductase (DHFR).

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