Abemaciclib metabol...

Abemaciclib metabolite M2

Abemaciclib metabolite M2

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LSN2839567 5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzimidazol-6-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-2-pyrimidinamine

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Abemaciclib metabolite M2, a metabolite of Abemaciclib, is a potent inhibitor of CDK4 and CDK6 with IC50s of 1-3 nM. It has anticancer activity.

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