ABT-546

Min.Order / FOB Price:Get Latest Price

0	Negotiable

Product Details
Company Profile

Min.Order :0
Purity: 95%

Keywords

A-216546 free base 3-Pyrrolidinecarboxylic acid, 1-(2-(dibutylamino)-2-oxoethyl)-2-(2,2-dimethylpentyl)-4-(7-methoxy-1,3-benzodioxol-5-yl)-, (2S,3R,4S)-

Quick Details

Appearance:
Application:For research use only.
PackAge:
ProductionCapacity:
Storage:
Transportation:

Superiority:

We provide customized and high-quality ABT-546 product for your project.

Details:

ABT-546 is a potent, highly selective and active antagonist of ETA receptor with a Ki of 0.46 nM for [125I]endothelin-1 binding to cloned human ETA. It is >25,000-fold more selectivity for ETA receptor than ETB receptor. It blocks endothelin-1-induced arachidonic acid release and phosphatidylinositol hydrolysis with IC50s of 0.59 and 3 nM, respectively.

View All