Alobresib

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GS-5829

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Alobresib is a novel BET bromodomain inhibitor. Alobresib reversibly binds the BET bromodomain proteins BRD2, BRD3, BRD4, and BRDT and prevents protein-protein interaction between BET proteins and acetylated histones and transcription factors, against multiple primary USC cell lines overexpressing c-Myc.

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