Anpirtoline

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Purity: ≥95%

Keywords

Pyridine, 2-chloro-6-(4-piperidinylthio)- 2-Chloro-6-(4-piperidinylthio)pyridine

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Appearance:Solid
Application:For research use only.
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Storage:Store at -20°C
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Anpirtoline is a highly potent 5-HT1B receptor agonist with a Ki value of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptor with a Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents.

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