Antipain dihydrochloride from microbial source N-(Nα-Carbonyl-Arg-Val-Arg-al)-Phe
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Antipain dihydrochloride, a protease inhibitor isolated from Actinomycetes, inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberration. It restricts DNA synthesis and function of mice uterus.
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