Arachidonoyl-2'-fluoroethylamide

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Purity: ≥98%

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2'-fluoro AEA 2'-fluoro Anandamide

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Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. Arachidonoyl 2'-fluoroethylamide is a CB1 receptor agonist with Ki of 26.7 nM for CB1 and Ki of 908 nM for CB2. The in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH.

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