3,5-Diethyl 1,4-dihydro-2,6-dimethyl-2,6-dimethyl-3,4,5-pyridinetricarboxylate monosodium salt 3,4,5-Pyridinetricarboxylic acid, 1,4-dihydro-2,6-dimethyl-2,6-dimethyl-, 3,5-diethyl ester, monosodium salt
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AV-153, a derivative of 1,4-dihydropyridine (1,4-DHP), has antimutagenic and anticancer activity. It intercalates to DNA in a single strand break, reduces DNA damage and stimulates DNA repair in human cells in vitro. It interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation.
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