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AZ12672857
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AZ12672857 is an orally active inhibitor of EphB4 and Src kinases. It shows potent inhibition of proliferation of c-Src transfected 3T3 cells (IC50 = 2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC50 = 9 nM).
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