AZ6102

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Purity: 95%

Keywords

2-[4-[6-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl]phenyl]-7-methyl-1H-pyrrolo[2,3-d]pyrimidin-4-oneAZ6102 AZ-6102

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Appearance:Solid powder
Application:For research use only.
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Storage:Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -53°C for long term (months to years).
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Details:

AZ6102 is a moderate oral bioavailable dual inhibitor of TNKS1/2 with excellent selectivity against other PARP family enzymes including PARP-1, PARP-2 and PARP-6. It also inhibits Wnt signaling in DLD-1 cells.
IC50: TNKS2= 1 nM; TNKS1= 3 nM; Wnt signaling

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