8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one AZD0156
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AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage checkpoint activation, and disrupts DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells.
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