Barbadin

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Purity: 99%

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3-Amino-5-(4-benzylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one

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Barbadin is a selective β-arrestin/β2-adaptin interaction inhibitor. It blocks agonist-promoted endocytosis of the prototypical β2-adrenergic (β2AR), V2-vasopressin (V2R) and angiotensin-II type-1 (AT1R) receptors, but does not affect β-arrestin-independent (transferrin) or AP2-independent (endothelin-A) receptor internalization.

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