BRL 44408

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Purity: ≥95%

Keywords

2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole 1H-Isoindole, 2-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-

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Appearance:Off-white Solid
Application:Selective α2A-adrenoceptor antagonist . Increases hippocampal noradrenaline release following systemic administration.
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BRL 44408 is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors, respectively). BRL 44408 increases hippocampal noradrenalin release following systemic administration.

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