CAY 10578 CAY-10578
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Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. Deregulation of CK2 has been linked to tumorigenesis as a potential protection mechanism for mutated cells. CAY10578 is a potent inhibitor of CK2 with IC50 value of 0.3 μM. It is ATP competitive and displays Ki value of 0.2 μM.
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