CAY 10595 CAY-10595
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Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) is a G-protein coupled receptor that binds to the ligand prostaglandin D2 (PGD2).The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP2 receptor antagonist with Ki of 10 nM.
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