CB096

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Purity: 99%

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2-Methoxy-4-(5-nitro-1H-benzo[d]imidazol-2-yl)phenol

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CB096 selectively inhibited repeat associated non-ATG (RAN) translation and decreased the production of poly(GP) DPRs without affecting r(G4C2)66 mRNA levels in an HEK293T cellular model of c9ALS/FTD, alleviated dysfunctional nucleocytoplasmic transport, and selectively reduced the abundance of r(G4C2)66-induced stress granules.

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