CBHA

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Purity: ≥98%

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Histone Deacetylase Inhibitor II m-Carboxycinnamic acid bis-hydroxamide

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Appearance:Off-white Solid
Application:Histone Deacetylase Inhibitors
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Histone deacetylase (HDAC) inhibitors hyperacetylate histones and increase transcriptional activity in selected genes. CBHA is a cell-permeable second generation hybrid polar agent that acts as a HDAC inhibitor. It exhibits ID50 values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively. CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture.

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