CasNo.268725-86-6,CFM 1571,1H-Pyrazole-5-carboxamide, 3-(3-(dimethylamino)propoxy)-N-(4-methoxyphenyl)-1-(phenylmethyl)-(268725-86-6) Suppliers

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Purity: ≥95%

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3-[3-(Dimethylamino)propoxy]-N-(4-methoxyphenyl)-1-(phenylmethyl)-1H-pyrazole-5-carboxamide 1H-Pyrazole-5-carboxamide, 3-(3-(dimethylamino)propoxy)-N-(4-methoxyphenyl)-1-(phenylmethyl)-

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Appearance:Off-white Solid
Application:For research use only.
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Storage:Store at 2-8°C
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CFM 1571 is a stimulator of nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC50 of 5.49 μM and IC50 of 2.84 μM. When adenylyl cyclase is not activated, it has no obvious inhibition on phosphodiesterases, and shows minimal inhibition of iNOS (25%) and nNOS (17%). It inhibits collagen-stimulated platelet aggregation in vitro (IC50 = 2.84 μM), and has the potential to study cardiovascular and other diseases.