Claficapavir

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Purity: >98% (HPLC)

Keywords

A1752 3-Thiazolidinepropanoic acid, 5-[[5-(4-chlorophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-, (5Z)-

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Appearance:Solide Powder
Application:For research use only.
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Storage:Powder: -20°C 4 months 4°C 6 months In solvent: -80°C 6 months -20°C 1 months
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Claficapavir, a specific nucleocapsid protein (NC) inhibitor with an IC50 of about 1 μM, strongly binds to HIV-1 NC (Kd = 20 nM) thereby inhibiting the chaperone properties of NC and resulting in good antiviral activity against HIV-1.

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