Cobimetinib hemifumarate

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Methanone, [3,?4-?difluoro-?2-?[(2-?fluoro-?4-?iodophenyl)?amino]?phenyl]?[3-?hydroxy-?3-?(2S)?-?2-?piperidinyl-?1-?azetidinyl]?-?, (2E)?-?2-?butenedioate (2:1)

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Cobimetinib, also known as GDC-0973 and XL-518, is a novel selective MEK inhibitor, and the IC50value against MEK1 is 4.2 nM, with potential antineoplastic activity.

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